If you are going to manually organise your fonts first decide on a strategy for your font library. You should centralise your fonts into one location. Make a new folder in /Users/Shared and call it My Fonts. Within this folder you can implement your chosen strategy. Here are some suggestions:
Alphabetically by name
This is often the easiest
way to find a particular font. If using this method you
could add subfolders within the My
Fonts folder, for example
This strategy can be used
by those experienced in typography. You could set up
subfolders such as Serif,
Often used in production
environments you could create a set of subfolders for each
job or magazine title that you are responsible for.
With font management software fonts can be activated and
de-activated from this location as they are needed.
Fonts that are stored in the areas described on the Font
locations page are typically managed by the operating
system and not your font management software, so it is time
to tidy up those fonts.